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Characterization of the novel nitric oxide synthase inhibitor 7-nitro indazole and related indazoles: antinociceptive and cardiovascular effects.

1. 7-Nitro indazole (7-NI, 10-50 mg kg-1), 6-nitro indazole and indazole (25-100 mg kg-1) administered i.p. in the mouse produce dose-related antinociception in the late phase of the formalin-induced hindpaw licking and acetic acid-induced abdominal constriction assays. The ED50 values (mg kg-1) wer...

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書誌詳細
主要な著者: Moore, P. K., Wallace, P., Gaffen, Z., Hart, S. L., Babbedge, R. C.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175981/
https://ncbi.nlm.nih.gov/pubmed/7693278
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