Effect of the platelet-activating factor antagonist, TCV-309, and the cyclo-oxygenase inhibitor, ibuprofen, on the haemodynamic changes in canine experimental endotoxic shock.

1. The present study was conducted in order to examine the effects of the platelet-activating factor (PAF) antagonist, TCV-309, and the cyclo-oxygenase inhibitor, ibuprofen, on the acute haemodynamic responses to endotoxin in anaesthetized dogs. 2. Endotoxin (2 mg kg-1, i.v.) induced a severe hypote...

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Hauptverfasser: Yamanaka, S., Iwao, H., Yukimura, T., Kim, S., Miura, K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1993
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175868/
https://ncbi.nlm.nih.gov/pubmed/8306093
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