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Regional haemodynamic responses to intravenous and intraarterial endothelin-1 and big endothelin-1 in conscious rats.

1. In the same chronically-instrumented conscious Long Evans rats, we assessed regional haemodynamic responses to i.v. and i.a. injections of endothelin-1 (ET-1) and big endothelin-1 at doses of 0.05 (n = 4) and 0.5 nmol kg-1 (n = 7). 2. For ET-1, the cardiovascular effects (initial hypotension and...

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Main Authors: Gardiner, S. M., Kemp, P. A., Bennett, T.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1993
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175838/
https://ncbi.nlm.nih.gov/pubmed/8306098
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