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Trimethoprim-induced DNA polymerase I deficiency in Escherichia coli K-12.

Curing of the mini-ColE1 plasmid pML21 was observed among cells of Escherichia coli K-12 strain C600(pML21) grown under subinhibitory conditions in the presence of trimethoprim, a specific inhibitor of dihydrofolate reductase. Some of the cured colonies showed (i) a reduction in frequency of transfo...

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Detalhes bibliográficos
Main Authors: Mukhopadhyay, P, Syrowik, U, Palchaudhuri, S
Formato: Artigo
Idioma:Inglês
Publicado em: 1983
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC217579/
https://ncbi.nlm.nih.gov/pubmed/6343343
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