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Inhibition by sumatriptan of central trigeminal neurones only after blood-brain barrier disruption.

1. The 5-hydroxytryptamine (5-HT1)-like agonist, sumatriptan, is highly efficient in the relief of migraine headache and its accompanying symptoms. 2. Experimental evidence has indicated that its site of action may be on the cranial vessels or on the trigeminal innervation of the cranium, or both, s...

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Autors principals: Kaube, H., Hoskin, K. L., Goadsby, P. J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175651/
https://ncbi.nlm.nih.gov/pubmed/8395298
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