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Low Levels of RNase H Activity in Escherichia coli FB2 rnh Result from a Single-Base Change in the Structural Gene of RNase H

The DNA coding for RNase H from a mutant strain of Escherichia coli (FB2) was cloned into plasmid pBR322. DNA sequence analysis and the exchange of a portion of the mutant and wild-type genes revealed that a single-base alteration (C→T) in the coding region of the structural gene for RNase H is resp...

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Dettagli Bibliografici
Pubblicato in:J Bacteriol
Autori principali: Kanaya, Shigenori, Crouch, Robert J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1983
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC217564/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6302075/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.154.2.1021-1026.1983
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