The action of amlodipine on voltage-operated calcium channels in vascular smooth muscle.

1. Amlodipine, a dihydropyridine derivative largely ionized at physiological pH, inhibited calcium channel currents in single vascular smooth muscle cells isolated from rabbit ear artery in a concentration-dependent manner. 2. Amlodipine inhibited the current-voltage relationship for calcium channel...

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Main Authors: Hughes, A. D., Wijetunge, S.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175575/
https://ncbi.nlm.nih.gov/pubmed/8388295
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