Detection of TMPRSS2-ERG Translocations in Human Prostate Cancer by Expression Profiling Using GeneChip Human Exon 1.0 ST Arrays

Translocation of TMPRSS2 to the ERG gene, found in a high proportion of human prostate cancer, results in overexpression of the 3′-ERG sequences joined to the 5′-TMPRSS2 promoter. The studies presented here were designed to test the ability of expression analysis on GeneChip Human Exon 1.0 ST arrays...

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Главные авторы: Jhavar, Sameer, Reid, Alison, Clark, Jeremy, Kote-Jarai, Zsofia, Christmas, Timothy, Thompson, Alan, Woodhouse, Christopher, Ogden, Christopher, Fisher, Cyril, Corbishley, Cathy, De-Bono, Johann, Eeles, Rosalind, Brewer, Daniel, Cooper, Colin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2008
Предметы:
Technical Advance
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175543/
https://ncbi.nlm.nih.gov/pubmed/18165275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2008.070085
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