Inhibition of Influenza M2-Induced Cell Death Alleviates Its Negative Contribution to Vaccination Efficiency

The effectiveness of recombinant vaccines encoding full-length M2 protein of influenza virus or its ectodomain (M2e) have previously been tested in a number of models with varying degrees of success. Recently, we reported a strong cytotoxic effect exhibited by M2 on mammalian cells in vitro. Here we...

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Main Authors: Ilyinskii, Petr O., Gambaryan, Alexandra S., Meriin, Anatoli B., Gabai, Vladimir, Kartashov, Alex, Thoidis, Galini, Shneider, Alexander M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175529/
https://ncbi.nlm.nih.gov/pubmed/18197240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001417
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