Sequence variation and linkage disequilibrium in the GABA transporter-1 gene (SLC6A1) in five populations: implications for pharmacogenetic research

BACKGROUND: GABA transporter-1 (GAT-1; genetic locus SLC6A1) is emerging as a novel target for treatment of neuropsychiatric disorders. To understand how population differences might influence strategies for pharmacogenetic studies, we identified patterns of genetic variation and linkage disequilibr...

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Detalhes bibliográficos
Main Authors: Hirunsatit, Rungnapa, Ilomäki, Risto, Malison, Robert, Räsänen, Pirkko, Ilomäki, Essi, Kranzler, Henry R, Kosten, Thomas, Sughondhabirom, Atapol, Thavichachart, Nuntika, Tangwongchai, Sookjaroen, Listman, Jennifer, Mutirangura, Apiwat, Gelernter, Joel, Lappalainen, Jaakko
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175509/
https://ncbi.nlm.nih.gov/pubmed/17941974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-8-71
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