Pharmacokinetic analysis of two different docetaxel dose levels in patients with non-small cell lung cancer treated with docetaxel as monotherapy or with concurrent radiotherapy

BACKGROUND: Previous pharmacokinetic studies with docetaxel have mostly used 3-weekly (75 mg/m(2 )and 100 mg/m(2)) or weekly regimens (35–40 mg/m(2)). The pharmacokinetics and radiosensitizing efficacy of weekly 20 mg/m(2 )docetaxel, has however not been well characterized. We examined the pharmacok...

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Main Authors: Fr Brunsvig, Paal, Andersen, Anders, Aamdal, Steinar, Kristensen, Vessela, Olsen, Harald
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175508/
https://ncbi.nlm.nih.gov/pubmed/17956601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-197
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