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Loss of housekeeping selenoprotein expression in mouse liver modulates lipoprotein metabolism

Selenium is incorporated into proteins as selenocysteine (Sec), which is dependent on its specific tRNA, designated tRNA([Ser]Sec). Targeted removal of the tRNA([Ser]Sec) gene (Trsp) in mouse hepatocytes previously demonstrated the importance of selenoproteins in liver function. Herein, analysis of...

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Auteurs principaux: Sengupta, Aniruddha, Carlson, Bradley A., Hoffmann, Victoria J., Gladyshev, Vadim N., Hatfield, Dolph L.
Format: Artigo
Langue:Inglês
Publié: 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175387/
https://ncbi.nlm.nih.gov/pubmed/17996733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2007.10.189
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