Ładuje się......
Deficiency of RecA-dependent RecFOR and RecBCD pathways causes increased instability of the (GAA·TTC)(n) sequence when GAA is the lagging strand template
The most common mutation in Friedreich ataxia is an expanded (GAA·TTC)(n) sequence, which is highly unstable in human somatic cells and in the germline. The mechanisms responsible for this genetic instability are poorly understood. We previously showed that cloned (GAA·TTC)(n) sequences replicated i...
Zapisane w:
| Główni autorzy: | , , , |
|---|---|
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2007
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2175318/ https://ncbi.nlm.nih.gov/pubmed/17932052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm810 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|