An engineered l-arginine sensor of Chlamydia pneumoniae enables arginine-adjustable transcription control in mammalian cells and mice

For optimal compatibility with biopharmaceutical manufacturing and gene therapy, heterologous transgene control systems must be responsive to side-effect-free physiologic inducer molecules. The arginine-inducible interaction of the ArgR repressor and the ArgR-specific ARG box, which synchronize argi...

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Hlavní autoři: Hartenbach, Shizuka, Daoud-El Baba, Marie, Weber, Wilfried, Fussenegger, Martin
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2007
Témata:
Methods Online
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175317/
https://ncbi.nlm.nih.gov/pubmed/17947334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm652
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