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Binding of the Mex67p/Mtr2p Heterodimer to Fxfg, Glfg, and Fg Repeat Nucleoporins Is Essential for Nuclear mRNA Export

It is not known how Mex67p and Mtr2p, which form a heterodimer essential for mRNA export, transport mRNPs through the nuclear pore. Here, we show that the Mex67p/Mtr2p complex binds to all of the repeat types (GLFG, FXFG, and FG) found in nucleoporins. For this interaction, complex formation between...

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Autors principals: Sträßer, Katja, Baßler, Jochen, Hurt, Ed
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175290/
https://ncbi.nlm.nih.gov/pubmed/10952996
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