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Dynamin:Gtp Controls the Formation of Constricted Coated Pits, the Rate Limiting Step in Clathrin-Mediated Endocytosis

The GTPase dynamin is essential for receptor-mediated endocytosis, but its function remains controversial. A domain of dynamin, termed the GTPase effector domain (GED), controls dynamin's high stimulated rates of GTP hydrolysis by functioning as an assembly-dependent GAP. Dyn(K694A) and dyn(R72...

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Détails bibliographiques
Auteurs principaux: Sever, Sanja, Damke, Hanna, Schmid, Sandra L.
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2000
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175254/
https://ncbi.nlm.nih.gov/pubmed/10974001
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