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Functional Analysis of Tpr: Identification of Nuclear Pore Complex Association and Nuclear Localization Domains and a Role in mRNA Export

Tpr is a 270-kD coiled-coil protein localized to intranuclear filaments of the nuclear pore complex (NPC). The mechanism by which Tpr contributes to the structure and function of the nuclear pore is currently unknown. To gain insight into Tpr function, we expressed the full-length protein and severa...

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Detalhes bibliográficos
Main Authors: Bangs, Peter, Burke, Brian, Powers, Christine, Craig, Roger, Purohit, Aruna, Doxsey, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175216/
https://ncbi.nlm.nih.gov/pubmed/9864356
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