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Three Regions within Acta Promote Arp2/3 Complex-Mediated Actin Nucleation and Listeria monocytogenes Motility

The Listeria monocytogenes ActA protein induces actin-based motility by enhancing the actin nucleating activity of the host Arp2/3 complex. Using systematic truncation analysis, we identified a 136-residue NH(2)-terminal fragment that was fully active in stimulating nucleation in vitro. Further dele...

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Autors principals: Skoble, Justin, Portnoy, Daniel A., Welch, Matthew D.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175181/
https://ncbi.nlm.nih.gov/pubmed/10931865
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