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Ephrin-A5 Induces Collapse of Growth Cones by Activating Rho and Rho Kinase

The ephrins, ligands of Eph receptor tyrosine kinases, have been shown to act as repulsive guidance molecules and to induce collapse of neuronal growth cones. For the first time, we show that the ephrin-A5 collapse is mediated by activation of the small GTPase Rho and its downstream effector Rho kin...

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Autores principales: Wahl, Siegfried, Barth, Holger, Ciossek, Thomas, Aktories, Klaus, Mueller, Bernhard K.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175154/
https://ncbi.nlm.nih.gov/pubmed/10769020
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