Llwytho...

Inhibitors of Copi and Copii Do Not Block PEX3-Mediated Peroxisome Synthesis

In humans, defects in peroxisome biogenesis are the cause of lethal diseases typified by Zellweger syndrome. Here, we show that inactivating mutations in human PEX3 cause Zellweger syndrome, abrogate peroxisome membrane synthesis, and result in reduced abundance of peroxisomal membrane proteins (PMP...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: South, Sarah T., Sacksteder, Katherine A., Li, Xiaoling, Liu, Yifei, Gould, Stephen J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2000
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175136/
https://ncbi.nlm.nih.gov/pubmed/10871277
Tagiau: Ychwanegu Tag
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