A Family of Proteins with γ-Adaptin and Vhs Domains That Facilitate Trafficking between the Trans-Golgi Network and the Vacuole/Lysosome

We have cloned and characterized members of a novel family of proteins, the GGAs. These proteins contain an NH(2)-terminal VHS domain, one or two coiled-coil domains, and a COOH-terminal domain homologous to the COOH-terminal “ear” domain of γ-adaptin. However, unlike γ-adaptin, the GGAs are not ass...

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Bibliographic Details
Main Authors: Hirst, Jennifer, Lui, Winnie W.Y., Bright, Nicholas A., Totty, Nicholas, Seaman, Matthew N.J., Robinson, Margaret S.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2000
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2175106/
https://ncbi.nlm.nih.gov/pubmed/10747088
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