Polyglycylation of Tubulin Is Essential and Affects Cell Motility and Division in Tetrahymena thermophila

We analyzed the role of tubulin polyglycylation in Tetrahymena thermophila using in vivo mutagenesis and immunochemical analysis with modification-specific antibodies. Three and five polyglycylation sites were identified at glutamic acids near the COOH termini of α- and β-tubulin, respectively. Muta...

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Main Authors: Xia, Lu, Hai, Bing, Gao, Yan, Burnette, Dylan, Thazhath, Rupal, Duan, Jianming, Bré, Marie-Helene, Levilliers, Nicolette, Gorovsky, Martin A., Gaertig, Jacek
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2000
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174830/
https://ncbi.nlm.nih.gov/pubmed/10831613
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