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Selective Growth, In Vitro and In Vivo, of Individual T Cell Clones from Tumor-Infiltrating Lymphocytes Obtained from Patients with Melanoma

In recent clinical trials in patients with metastatic melanoma, adoptive transfer of tumor-reactive lymphocytes mediated the regression of metastatic tumor deposits. To better understand the role of individual T cell clones in mediating tumor regression, a 5′ RACE technique was used to determine the...

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Main Authors: Zhou, Juhua, Dudley, Mark E., Rosenberg, Steven A., Robbins, Paul F.
格式: Artigo
語言:Inglês
出版: 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174603/
https://ncbi.nlm.nih.gov/pubmed/15585890
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