Optimal ex vivo expansion of neutrophils from PBSC CD34(+ )cells by a combination of SCF, Flt3-L and G-CSF and its inhibition by further addition of TPO

BACKGROUND: Autologous mobilised peripheral blood stem cell (PBSC) transplantation is now a standard approach in the treatment of haematological diseases to reconstitute haematopoiesis following myeloablative chemotherapy. However, there remains a period of severe neutropenia and thrombocytopenia be...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Tura, Olga, Barclay, G Robin, Roddie, Huw, Davies, John, Turner, Marc L
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2007
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174439/
https://ncbi.nlm.nih.gov/pubmed/17971220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-5-53
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