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Optimal ex vivo expansion of neutrophils from PBSC CD34(+ )cells by a combination of SCF, Flt3-L and G-CSF and its inhibition by further addition of TPO
BACKGROUND: Autologous mobilised peripheral blood stem cell (PBSC) transplantation is now a standard approach in the treatment of haematological diseases to reconstitute haematopoiesis following myeloablative chemotherapy. However, there remains a period of severe neutropenia and thrombocytopenia be...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2174439/ https://ncbi.nlm.nih.gov/pubmed/17971220 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-5-53 |
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