Cooh-Terminal Truncations Promote Proteasome-Dependent Degradation of Mature Cystic Fibrosis Transmembrane Conductance Regulator from Post-Golgi Compartments

Impaired biosynthetic processing of the cystic fibrosis (CF) transmembrane conductance regulator (CFTR), a cAMP-regulated chloride channel, constitutes the most common cause of CF. Recently, we have identified a distinct category of mutation, caused by premature stop codons and frameshift mutations,...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Benharouga, Mohamed, Haardt, Martin, Kartner, Norbert, Lukacs, Gergely L.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2001
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174331/
https://ncbi.nlm.nih.gov/pubmed/11381082
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky