Membrane-Type 1 Matrix Metalloproteinase Cleaves Cd44 and Promotes Cell Migration

Migratory cells including invasive tumor cells frequently express CD44, a major receptor for hyaluronan and membrane-type 1 matrix metalloproteinase (MT1-MMP) that degrades extracellular matrix at the pericellular region. In this study, we demonstrate that MT1-MMP acts as a processing enzyme for CD4...

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Detalhes bibliográficos
Main Authors: Kajita, Masahiro, Itoh, Yoshifumi, Chiba, Tadashige, Mori, Hidetoshi, Okada, Akiko, Kinoh, Hiroaki, Seiki, Motoharu
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174329/
https://ncbi.nlm.nih.gov/pubmed/11381077
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