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Activation of the Met Receptor by Cell Attachment Induces and Sustains Hepatocellular Carcinomas in Transgenic Mice

Overexpression is the most common abnormality of receptor tyrosine kinases (RTKs) in human tumors. It is presumed that overexpression leads to constitutive activation of RTKs, but the mechanism of that activation has been uncertain. Here we show that overexpression of the Met RTK allows activation o...

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Bibliografische gegevens
Hoofdauteurs: Wang, Rong, Ferrell, Linda D., Faouzi, Saadia, Maher, Jacquelyn J., Bishop, J. Michael
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174327/
https://ncbi.nlm.nih.gov/pubmed/11381087
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