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Alternative Splicing Regulates the Subcellular Localization of a-Kinase Anchoring Protein 18 Isoforms

The cAMP-dependent protein kinase (PKA) is localized to specific subcellular compartments by association with A-kinase anchoring proteins (AKAPs). AKAPs are a family of functionally related proteins that bind the regulatory (R) subunit of PKA with high affinity and target the kinase to specific subc...

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Main Authors: Trotter, Kevin W., Fraser, Iain D.C., Scott, Gregory K., Stutts, M. Jackson, Scott, John D., Milgram, Sharon L.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174236/
https://ncbi.nlm.nih.gov/pubmed/10613906
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