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A Cell-Free Assay System for β-Catenin Signaling That Recapitulates Direct Inductive Events in the Early Xenopus laevis Embryo

In vertebrate embryos, signaling via the β-catenin protein is known to play an essential role in the induction of the dorsal axis. In its signaling capacity, β-catenin acts directly to affect target gene transcription, in concert with transcription factors of the TCF/LEF family. We have developed a...

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Autors principals: Nelson, Richard W., Gumbiner, Barry M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174222/
https://ncbi.nlm.nih.gov/pubmed/10525541
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