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Quaternary Structure of the Mitochondrial TIM23 Complex Reveals Dynamic Association between Tim23p and Other Subunits

Tim23p is an essential channel-forming component of the multisubunit TIM23 complex of the mitochondrial inner membrane that mediates protein import. Radiolabeled Tim23p monocysteine mutants were imported in vitro, incorporated into functional TIM23 complexes, and subjected to chemical cross-linking....

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Bibliographische Detailangaben
Hauptverfasser: Alder, Nathan N., Sutherland, Jennifer, Buhring, Ashley I., Jensen, Robert E., Johnson, Arthur E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2008
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174187/
https://ncbi.nlm.nih.gov/pubmed/17959826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-07-0669
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