Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule?

Fluid shear stress (FSS) induces many forms of responses, including phosphorylation of extracellular signal–regulated kinase (ERK) in endothelial cells (ECs). We have earlier reported rapid tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1) in ECs exposed to FSS. Osm...

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Autors principals: Osawa, Masaki, Masuda, Michitaka, Kusano, Ken-ichi, Fujiwara, Keigi
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2174013/
https://ncbi.nlm.nih.gov/pubmed/12177047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200205049
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