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The Cdc37 protein kinase–binding domain is sufficient for protein kinase activity and cell viability

Cdc37 is a molecular chaperone required for folding of protein kinases. It functions in association with Hsp90, although little is known of its mechanism of action or where it fits into a folding pathway involving other Hsp90 cochaperones. Using a genetic approach with Saccharomyces cerevisiae, we s...

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Detalhes bibliográficos
Main Authors: Lee, Paul, Rao, Jie, Fliss, Albert, Yang, Emy, Garrett, Stephen, Caplan, Avrom J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173992/
https://ncbi.nlm.nih.gov/pubmed/12499358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200210121
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