Compartmentalization of integrin α6β4 signaling in lipid rafts

Integrin α6β4 signaling proceeds through Src family kinase (SFK)–mediated phosphorylation of the cytoplasmic tail of β4, recruitment of Shc, and activation of Ras and phosphoinositide-3 kinase. Upon cessation of signaling, α6β4 mediates assembly of hemidesmosomes. Here, we report that part of α6β4 i...

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Main Authors: Gagnoux-Palacios, Laurent, Dans, Michael, van't Hof, Wouter, Mariotti, Agnese, Pepe, Angela, Meneguzzi, Guerrino, Resh, Marilyn D., Giancotti, Filippo G.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2003
Teme:
Report
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173954/
https://ncbi.nlm.nih.gov/pubmed/14517202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305006
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