Consequences of exclusive expression in vivo of kit-ligand lacking the major proteolytic cleavage site

Membrane growth factors that are processed to produce soluble ligands may function both as soluble factors and as membrane factors. The membrane growth factor Kit-ligand (KL), the ligand of the Kit receptor tyrosine kinase, is encoded at the Sl locus, and mice carrying Sl mutations have defects in h...

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Bibliographic Details
Main Authors: Tajima, Youichi, Moore, Malcolm A. S., Soares, Vera, Ono, Masao, Kissel, Holger, Besmer, Peter
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1998
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC21738/
https://ncbi.nlm.nih.gov/pubmed/9751763
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