The stromal cell–derived factor-1α/CXCR4 ligand–receptor axis is critical for progenitor survival and migration in the pancreas

The SDF-1α/CXCR4 ligand/chemokine receptor pair is required for appropriate patterning during ontogeny and stimulates the growth and differentiation of critical cell types. Here, we demonstrate SDF-1α and CXCR4 expression in fetal pancreas. We have found that SDF-1α and its receptor CXCR4 are expres...

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Hauptverfasser: Kayali, Ayse G., Van Gunst, Kurt, Campbell, Iain L., Stotland, Aleksandr, Kritzik, Marcie, Liu, Guoxun, Flodström-Tullberg, Malin, Zhang, You-Qing, Sarvetnick, Nora
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2003
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173676/
https://ncbi.nlm.nih.gov/pubmed/14638861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304153
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