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The Drosophila nucleoporin DNup88 localizes DNup214 and CRM1 on the nuclear envelope and attenuates NES-mediated nuclear export

Many cellular responses rely on the control of nucleocytoplasmic transport of transcriptional regulators. The Drosophila nucleoporin Nup88 is selectively required for nuclear accumulation of Rel proteins and full activation of the innate immune response. Here, we investigate the mechanisms underlyin...

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Detalhes bibliográficos
Main Authors: Roth, Peggy, Xylourgidis, Nikos, Sabri, Nafiseh, Uv, Anne, Fornerod, Maarten, Samakovlis, Christos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173670/
https://ncbi.nlm.nih.gov/pubmed/14638854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200304046
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