IGF-II transcription in skeletal myogenesis is controlled by mTOR and nutrients

Insulin-like growth factors (IGFs) are essential for skeletal muscle development, regeneration, and hypertrophy. Although autocrine actions of IGF-II are known to initiate myoblast differentiation, the regulatory elements and upstream signaling pathways for myogenic expression of IGF-II remain elusi...

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Main Authors: Erbay, Ebru, Park, In-Hyun, Nuzzi, Paul D., Schoenherr, Christopher J., Chen, Jie
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173600/
https://ncbi.nlm.nih.gov/pubmed/14662739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200307158
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