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Regulation of TrkB receptor tyrosine kinase and its internalization by neuronal activity and Ca(2+) influx

Internalization of the neurotrophin–Trk receptor complex is critical for many aspects of neurotrophin functions. The mechanisms governing the internalization process are unknown. Here, we report that neuronal activity facilitates the internalization of the receptor for brain-derived neurotrophic fac...

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Detalhes bibliográficos
Main Authors: Du, Jing, Feng, Linyin, Zaitsev, Eugene, Je, Hyun-Soo, Liu, Xu-wen, Lu, Bai
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173520/
https://ncbi.nlm.nih.gov/pubmed/14581459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305134
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