The Listeria monocytogenes hemolysin has an acidic pH optimum to compartmentalize activity and prevent damage to infected host cells

Listeria monocytogenes is a facultative intracellular bacterial pathogen that escapes from a phagosome and grows in the host cell cytosol. The pore-forming cholesterol-dependent cytolysin, listeriolysin O (LLO), mediates bacterial escape from vesicles and is ∼10-fold more active at an acidic than ne...

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Detaylı Bibliyografya
Asıl Yazarlar: Glomski, Ian J., Gedde, Margaret M., Tsang, Albert W., Swanson, Joel A., Portnoy, Daniel A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2002
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173464/
https://ncbi.nlm.nih.gov/pubmed/11901168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200201081
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