H2AX regulates meiotic telomere clustering

The histone H2A variant H2AX is phosphorylated in response to DNA double-strand breaks originating from diverse origins, including dysfunctional telomeres. Here, we show that normal mitotic telomere maintenance does not require H2AX. Moreover, H2AX is dispensable for the chromosome fusions arising f...

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Bibliographic Details
Main Authors: Fernandez-Capetillo, Oscar, Liebe, Bodo, Scherthan, Harry, Nussenzweig, André
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173436/
https://ncbi.nlm.nih.gov/pubmed/14530383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200305124
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