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Cyclosporin A inhibits caspase-independent death of NGF-deprived sympathetic neurons: a potential role for mitochondrial permeability transition

Opening of the permeability transition pore (PTP) has been implicated as an important mitochondrial event that occurs during apoptosis. We examined the role of the PTP in the well-characterized cell death of rat sympathetic neurons deprived of nerve growth factor (NGF) in vitro. Removal of NGF cause...

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Autors principals: Chang, Louis K., Johnson, Eugene M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173417/
https://ncbi.nlm.nih.gov/pubmed/12021257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200112130
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