Tyrosine-phosphorylated and nonphosphorylated isoforms of α-dystrobrevin: roles in skeletal muscle and its neuromuscular and myotendinous junctions

α-Dystrobrevin (DB), a cytoplasmic component of the dystrophin–glycoprotein complex, is found throughout the sarcolemma of muscle cells. Mice lacking αDB exhibit muscular dystrophy, defects in maturation of neuromuscular junctions (NMJs) and, as shown here, abnormal myotendinous junctions (MTJs). In...

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Bibliographic Details
Main Authors: Grady, R. Mark, Akaaboune, Mohammed, Cohen, Alexander L., Maimone, Margaret M., Lichtman, Jeff W., Sanes, Joshua R.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2003
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173352/
https://ncbi.nlm.nih.gov/pubmed/12604589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200209045
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