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Disassembly of interchromatin granule clusters alters the coordination of transcription and pre-mRNA splicing
To examine the involvement of interchromatin granule clusters (IGCs) in transcription and pre-mRNA splicing in mammalian cell nuclei, the serine-arginine (SR) protein kinase cdc2-like kinase (Clk)/STY was used as a tool to manipulate IGC integrity in vivo. Both immunofluorescence and transmission el...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173333/ https://ncbi.nlm.nih.gov/pubmed/11827980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200107017 |
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