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In vivo dissection of the chromosome condensation machinery: reversibility of condensation distinguishes contributions of condensin and cohesin

The machinery mediating chromosome condensation is poorly understood. To begin to dissect the in vivo function(s) of individual components, we monitored mitotic chromosome structure in mutants of condensin, cohesin, histone H3, and topoisomerase II (topo II). In budding yeast, both condensation esta...

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Autori principali: Lavoie, Brigitte D., Hogan, Eileen, Koshland, Douglas
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2002
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173308/
https://ncbi.nlm.nih.gov/pubmed/11864994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200109056
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