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In vivo dissection of the chromosome condensation machinery: reversibility of condensation distinguishes contributions of condensin and cohesin

The machinery mediating chromosome condensation is poorly understood. To begin to dissect the in vivo function(s) of individual components, we monitored mitotic chromosome structure in mutants of condensin, cohesin, histone H3, and topoisomerase II (topo II). In budding yeast, both condensation esta...

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Bibliographic Details
Main Authors: Lavoie, Brigitte D., Hogan, Eileen, Koshland, Douglas
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173308/
https://ncbi.nlm.nih.gov/pubmed/11864994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200109056
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