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Intrinsic and extrinsic pathway signaling during neuronal apoptosis: lessons from the analysis of mutant mice

Trophic factor deprivation (TFD)-induced apoptosis in sympathetic neurons requires macromolecular synthesis–dependent BAX translocation, cytochrome c (cyt c) release, and caspase activation. Here, we report the contributions of other intrinsic and extrinsic pathway signals to these processes. Sympat...

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Autors principals: Putcha, Girish V., Harris, Charles A., Moulder, Krista L., Easton, Rachael M., Thompson, Craig B., Johnson, Eugene M.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173286/
https://ncbi.nlm.nih.gov/pubmed/11980919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200110108
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