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Phosphorylation and an ATP-dependent process increase the dynamic exchange of H1 in chromatin

In Tetrahymena cells, phosphorylation of linker histone H1 regulates transcription of specific genes. Phosphorylation acts by creating a localized negative charge patch and phenocopies the loss of H1 from chromatin, suggesting that it affects transcription by regulating the dissociation of H1 from c...

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Detalhes bibliográficos
Main Authors: Dou, Yali, Bowen, Josephine, Liu, Yifan, Gorovsky, Martin A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173238/
https://ncbi.nlm.nih.gov/pubmed/12356861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200202131
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