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T cell receptor ligation induces the formation of dynamically regulated signaling assemblies
Tcell antigen receptor (TCR) ligation initiates tyrosine kinase activation, signaling complex assembly, and immune synapse formation. Here, we studied the kinetics and mechanics of signaling complex formation in live Jurkat leukemic T cells using signaling proteins fluorescently tagged with variants...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2173229/ https://ncbi.nlm.nih.gov/pubmed/12356870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200203043 |
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