Localized Ca(2+) uncaging reveals polarized distribution of Ca(2+)-sensitive Ca(2+) release sites: mechanism of unidirectional Ca(2+) waves

Ca(2+)-induced Ca(2+) release (CICR) plays an important role in the generation of cytosolic Ca(2+) signals in many cell types. However, it is inherently difficult to distinguish experimentally between the contributions of messenger-induced Ca(2+) release and CICR. We have directly tested the CICR se...

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Main Authors: Ashby, Michael C., Craske, Madeleine, Park, Myoung Kyu, Gerasimenko, Oleg V., Burgoyne, Robert D., Petersen, Ole H., Tepikin, Alexei V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2173122/
https://ncbi.nlm.nih.gov/pubmed/12119355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200112025
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